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Vaccination isn't a perfect defense against flu. But vaccines remain the most reliable way to reduce the risk from an illness that causes thousands of deaths in the U.S. during a typical flu season.

Well-known artists and designers are taking over billboards (donated gratis) to brighten the landscape in an emptier-than-usual Times Square. One work simply reads: "Hopefully no one will see this."

The agency wants to shore up its supply in the wake of severe winter weather and the California wildfires. It says all blood types are needed, especially O negative.

NPR's Michel Martin speaks with three young Republican delegates about their party's convention, which took place this week: Jessi Rapelje, Hayden Padgett and Maria Vasquez.

We hold this truth to be self-evident: America loves pie. But each region also reserves the right to bake the treat in its own style. In United States of Pie, writer Adrienne Kane explores local takes on the ultimate American confection.

NPR's Scott Detrow speaks with Brian Raftery, author of the book, Best. Movie. Year. Ever.: How 1999 Blew Up the Big Screen.

The Studio, The Pitt and Adolescence took home top prizes on Sunday. And while the wins were deserving, the telecast was meh. Here are a few takeaways from a night that was a real mixed bag.

Columbus and Cincinnati have filed a lawsuit to halt increased electricity fees tied to HB6, the nuclear power plant bailout at the center of a federal...

The trial, at a courthouse just down the street from the site of the Jan. 6, 2021, insurrection, is a milestone in the Capitol riot investigation.

Melinda Penkava talks to Weekend Edition entertainment critic Elvis Mitchell about the new documentary, The Kings of Comedy. 6:00.