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Late Show host David Letterman said goodbye Wednesday night with his trademark self-deprecating sarcasm. He left as he had arrived: with a hilarious show made on his own terms.

The Millennium Development Goals, set in 2000, revolutionized the fight against poverty. Now the world is setting Sustainable Development Goals. But critics say there may be too many priorities.

Both candidates have said they are running positive campaigns, but that could change in this week's debate. In the past, they have shown a willingness to turn tough on their opponents.

Russian hackers tried a phishing scheme, a White House operator didn't believe the caller was actually Clinton and she panicked after being unable to find her local NPR station.

The latest session made history on several fronts, and accepted cases for next year that will likely make still more. This year the liberals won a lot — but that doesn't mean they will in the future.

In important Super Tuesday states with a high number of born-again voters, Ted Cruz is losing to Donald Trump, and Marco Rubio is eating into his support with evangelicals.

The record-breaking powerball prize rose to new heights this afternoon. But did you know Americans spent more than $70 billion on the lottery last year?

It wasn't what you think, but it was certainly a story. I was lucky enough to meet him a few times over several decades, but the first time was the most memorable.

NPR's Ailsa Chang talks with Rangina Hamidi, Afghanistan's acting minister of education, about what it's like on the ground in Kabul during the Taliban's latest military surge in the country.

Natalie McCray was 11 when her school went all-remote in March 2020. Now, at 13, she's returning to the classroom for the first time since the pandemic began.