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One of the biggest political questions of the year will be answered: Can Senate Minority Leader Mitch McConnell withstand a Tea Party challenge?

Clinton ended a nearly monthlong avoidance of press questions, addressing the release of her emails, foreign donations to the Clinton foundation, the state of Iraq and more.

Airstrikes have helped push back the Islamic State in some places, but the group has gained in other areas. Pentagon officials say the U.S. operation may need another two years or more to succeed.

Federal officials released prescription histories of hundreds of thousands of doctors and identified the most common and costly drugs. Medicare spent the most on a purple pill for heartburn.

Clean, safe drinking water is essential to life. To get that water, however, requires a sludge of chemicals, countless testings — and different treatment processes depending on where you live.

A small brigade of volunteers chopped up thousands of pounds of vegetables that might otherwise have landed in the dump. Celebrity chefs helped whip it into a meal tasty enough to get crowds to care.

Don't expect a parade of once-hopefuls trudging to microphones to quit the day after the caucuses. But the die will have been cast. Iowa doesn't kill candidacies; it puts them on life support.

The LA area is home to the most manufacturing jobs in the U.S., from clothes to metal parts to new aerospace tech. Companies have reinvented themselves, even as they struggle to find skilled workers.

The U.S. delivered the 200 millionth dose of COVID-19 vaccines worldwide, part of a 1.1 billion dose pledge. NPR's Steve Inskeep talks to the State Department's Gayle Smith, who is leading the effort.

Drive My Car tops Chang's list of the year's best movies, but plenty of other films made the return to theaters extra special.