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Penn got his start in stoner comedies, then took a hiatus from acting to work for the Obama administration. He shares stories from his life and career in the memoir You Can't Be Serious.

Area 51 is classified to the point that its very existence is denied by the U.S. government. Journalist Annie Jacobsen says it's not because of aliens or spaceships — but because the government used the site for nuclear testing and weapons development.

The next Cincinnati City Manager will not be on the job by the end of summer as planned. Finalists for the job were supposed to interview with City Council this month, but officials say that part of the process hasn’t started yet.

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared.

Taxpayers footed the bill for care that should have cost far less, according to records released under the Freedom of Information Act. The U.S. government may charge insurers $650 million as a result.

NPR's Mary Louise Kelly speaks with writer Kiese Laymon about what receiving a MacArthur Fellowship means to him and who shapes his writing.

Cincinnati City Council is considering major changes to the residential tax abatement program. A vote has been delayed four times for more community engagement, but that engagement has been lackluster at best.

The New York Times' David Brooks and the Washington Post's Ruth Marcus discuss the week in politics with Robert Siegel. On tap: Pennyslvania Sen. Bob Casey's endorsement of Sen. Barack Obama and Vermont Sen. Patrick Leahy's call for Sen. Hillary Clinton to drop out of the race.

A new Apple TV+ documentary profiles a man who appears to have found more joy as he's gotten older — and the more you watch this documentary, the more joy you'll find as well.

Georgia hasn’t expanded Medicaid. Some people suffer more than others because of that coverage gap.